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remark on ‘FinCen files’ reporting Amsterdam, a few media have in the past days posted reviews based on ‘suspicious recreation reviews’, filed a few years in the past. ING is mentioned in a number of these reviews. As a gatekeeper to the fiscal device, ING has a vital accountability to support protect customers, society and the fiscal system in opposition t economic financial crimes. here’s a problem the monetary business faces globally. ING takes its accountability extraordinarily seriously. during the last years, ING has taken many steps to boost the administration of compliance dangers and embed improved recognition throughout the total corporation. These steps are part of the a global programme which we now have been executing on account that 2017 in all markets that we are active in. The programme includes a collection of initiatives, which include enhancing customer files (KYC) and working on numerous structural improvements in compliance policies, tooling, monitoring, governance, and potential and behaviour. Over four,000 FTE are at the moment worried in our KYC efforts. As a part of our ongoing AML efforts ING invariably assesses relationships with purchasers and monitors transactions. doubtlessly suspicious transactions are reviewed and the place relevant pronounced to the vital authorities. over the past years we more and more discontinued consumer relationships. criminal requirements evade us from publicly disclosing additional details or specifics. we are frequently now not capable to touch upon individual circumstances. In some fresh media reviews although, ING is mentioned to have altered price instructions for a transaction in 2014 to disguise the identification of a sanctioned birthday celebration. ING wants to make clear that the mentioned sanctioned birthday celebration became now not a celebration to this price transaction. A reference to the sanctioned birthday celebration gave the impression to were erroneously added to one of the most device fields for the transaction. After discovery of this administrative error, the correct fee transaction was achieved. This has been mentioned with important US authorities in 2014 and no further action has been taken. fighting monetary crime can simplest be a success if banks, authorities, legislation enforcement and personal and public events join forces, on country wide and overseas tiers. Effectiveness is more desirable by way of shared intelligence, collaboration and third-birthday party partnerships, which is why we strongly help initiatives to jointly fight economic crime together, as gatekeepers of the fiscal industry. observe for editors For extra counsel on ING, please talk over with commonplace information updates can also be present in the Newsroom or via the @ING_news Twitter feed. photos of ING operations, buildings and its executives can be found for down load at Flickr. ING displays are available at SlideShare. ING PROFILE ING is a global fiscal institution with a powerful European base, offering banking features via its working enterprise ING financial institution. The purpose of ING bank is empowering people to dwell a step ahead in life and in business. ING financial institution’s more than 55,000 employees offer retail and wholesale banking features to valued clientele in over forty international locations. ING neighborhood shares are listed on the exchanges of Amsterdam (INGA NA, INGA.AS), Brussels and on the big apple stock change (ADRs: ING US, ING.N). Sustainability kinds a vital part of ING’s strategy, evidenced with the aid of ING’s leading place in sector benchmarks by using Sustainalytics and MSCI and our ‘A-checklist’ score via CDP. ING neighborhood shares are blanketed in principal sustainability and Environmental, Social and Governance (ESG) index items of leading providers STOXX, Morningstar and FTSE Russell. critical criminal guidance points of this press liberate comprise or may additionally contain suggestions about ING Groep N.V. and/ or ING financial institution N.V. inside the that means of Article 7(1) to (4) of eu legislation No 596/2014. definite of the statements contained herein aren’t ancient records, together with, with out obstacle, certain statements made of future expectations and other forward-searching statements which are in keeping with management’s present views and assumptions and contain widespread and unknown dangers and uncertainties that may trigger actual effects, performance or hobbies to vary materially from these expressed or implied in such statements. actual results, efficiency or hobbies may also range materially from those in such statements due to a few elements, together with, with out hindrance: (1) adjustments in well-known financial conditions, in selected economic circumstances in ING’s core markets, including adjustments affecting forex trade quotes, (2) the effects of the Covid-19 pandemic and connected response measures, together with lockdowns and go back and forth restrictions, on economic situations in countries through which ING operates, on ING’s enterprise and operations and on ING’s employees, shoppers and counterparties, (three) alterations affecting interest fee levels, (4) any default of an immense market participant and connected market disruption, (5) adjustments in efficiency of fiscal markets, including in Europe and establishing markets, (6) changes in the fiscal place and the future financial performance of the us, including potential penalties of a downgrade of the sovereign credit rating of the USA government, (7) consequences of the United Kingdom’s withdrawal from the eu Union, (eight) changes in or discontinuation of ‘benchmark’ indices, (9) inflation and deflation in our essential markets, (10) adjustments in circumstances in the credit score and capital markets often, including changes in borrower and counterparty creditworthiness, (eleven) failures of banks falling under the scope of state compensation schemes, (12) non-compliance with or adjustments in legal guidelines and regulations, including those monetary capabilities and tax laws, and the interpretation and application thereof, (13) geopolitical dangers, political instabilities and policies and actions of governmental and regulatory authorities, (14) ING’s capacity to meet minimal capital and different prudential regulatory necessities, (15) outcomes of present and future litigation, enforcement lawsuits, investigations or different regulatory movements, including claims by shoppers, (16) operational dangers, akin to gadget disruptions or failures, breaches of security, cyber-assaults, human error, alterations in operational practices or insufficient controls together with in appreciate of third parties with which we do enterprise, (17) dangers and challenges concerning cybercrime together with the consequences of cyber- attacks and alterations in legislation and law concerning cybersecurity and facts privacy, (18) adjustments in well-known competitive factors, (19) the inability to give protection to our intellectual property and infringement claims via third events, (20) changes in credit score scores, (21) company, operational, regulatory, attractiveness and different risks and challenges in reference to climate exchange, (22) inability to entice and hold key personnel, (23) future liabilities under described advantage retirement plans, (24) failure to control business hazards, together with in connection with use of fashions, use of derivatives, or protecting applicable policies and instructions, (25) alterations in capital and credit markets, together with interbank funding, in addition to client deposits, which supply the liquidity and capital required to fund our operations, (26) the other dangers and uncertainties particular within the most recent annual record of ING Groep N.V. (together with the chance elements contained therein) and ING’s extra recent disclosures, including press releases, which can be found on This doc may also comprise inactive textual addresses to information superhighway websites operated by means of us and third parties. Reference to such sites is made for counsel functions only, and counsel discovered at such sites is not incorporated by using reference into this document. ING doesn’t make any representation or assurance with appreciate to the accuracy or completeness of, or take any accountability for, any information found at any websites operated by means of third parties. ING specifically disclaims any liability with appreciate to any suggestions found at web sites operated via third parties. ING cannot be sure that websites operated with the aid of third parties remain available following the book of this doc, or that any information discovered at such websites will no longer change following the filing of this document. lots of these components are past ING’s manage. Any forward looking statements made by or on behalf of ING talk most effective as of the date they are made, and ING assumes no obligation to publicly replace or revise any ahead-looking statements, whether as a result of new guidance or for any other rationale. This document does not constitute a proposal to sell, or a solicitation of a proposal to purchase, any securities within the u.s. or any other jurisdiction. Silence Therapeutics publicizes instructions for changing Listed typical Shares into Nasdaq Listed ADSs Silence Therapeutics publicizes instructions for changing Listed standard Shares into Nasdaq Listed ADSs 8 September 2020 LONDON, Silence Therapeutics plc, intention:SLN and Nasdaq: SLN (“Silence” or “the company”) a frontrunner in the discovery,  construction and beginning of novel short interfering ribonucleic acid (siRNA) therapeutics for the medication of ailments with colossal unmet scientific need, these days one by one introduced that in reference to a catalogue of american Depositary Shares ("ADSs") representing general shares of nominal price of £0.05 every within the capital of the business ("ordinary Shares") on the Nasdaq Capital Market ("Nasdaq"), the us Securities and change fee has declared advantageous registration statements on form F-1 and F-6 with recognize to such securities, Nasdaq has accepted the ADSs for list, and ADSs are anticipated to be listed for buying and selling on such market beneath the symbol "SLN" on eight September 2020. This announcement is supposed to guide holders of regular Shares, which are admitted to buying and selling on purpose, the market operated with the aid of the London stock trade, during the procedure of exchanging ordinary Shares for ADSs, and to answer definite related frequently requested questions relevant to holders of the common Shares. For any further questions concerning the regular Share to advertisements exchange manner, please contact the business’s ads Depositary financial institution, The financial institution of new york Mellon: New YorkLondonStephen ReideJacek JankowskiTel: +1 212 815 2723Tel: +forty four 207 163 7427 Enquiries:
Silence Therapeutics plcIain Ross, executive ChairmanDr Rob Quinn, Chief economic OfficerTel:  +44 (0)20 3457 6900  Investec financial institution plc (Nominated Adviser and broker) Daniel Adams/Gary Clarence  Tel:  +forty four (0) 20 7597 5970European IRConsilium Strategic CommunicationsMary-Jane Elliott/Chris Welsh/Angela Graysilencetherapeutics@consilium-comms.comTel: +44 (0) 20 3709 5700US IRWestwicke PartnersPeter Tel: +1 (443) 213-0505 Notes to Editors About Silence TherapeuticsSilence Therapeutics is establishing a brand new era of drug treatments with the aid of harnessing the physique’s natural mechanism of RNA interference, or RNAi, to inhibit the expression of particular goal genes thought to play a task within the pathology of diseases with big unmet medical want. Silence’s proprietary know-how will also be used to engineer short interfering ribonucleic acids (siRNAs) that bind mainly to and silence, during the RNAi pathway, basically any gene in the human genome to which siRNA will also be delivered. Silence’s fully owned product candidates consist of SLN360 designed to address the excessive and regularly occurring unmet scientific want in reducing cardiovascular chance in americans born with excessive ranges of Lipoprotein(a) and SLN124 to address beta-thalassemia and myelodysplastic syndrome. Silence is also establishing SLN500 in partnership with Mallinckrodt pharmaceuticals to reduce the expression of the C3 protein for the medicine of complement pathway-mediated ailments.  Silence keeps ongoing analysis and collaborations with AstraZeneca, Mallinckrodt prescribed drugs and Takeda. For more information, please visit: This announcement does not represent an offer to promote or the solicitation of a proposal to buy securities, and shall no longer represent a proposal, solicitation or sale in any jurisdiction during which such present, solicitation or sale could be illegal previous to registration or qualification beneath the securities laws of that jurisdiction. A prospectus describing the securities could be obtained from Silence Therapeutics plc at 27 Eastcastle street, London, W1W 8DH. For the avoidance of doubt, such prospectus doesn’t represent a "prospectus" for the functions of law (ecu) 2017/1129 and has now not been reviewed by any able authority in the united kingdom or any european member state. ahead-looking StatementsCertain statements made during this announcement are ahead-searching statements including with respect to the introduction of a buying and selling marketplace for ADSs representing the company’s usual Shares in the united states. These ahead-searching statements aren’t historical records but fairly are in response to the enterprise’s current expectations, estimates, and projections about its trade; its beliefs; and assumptions.  phrases reminiscent of ‘anticipates,’ ‘expects,’ ‘intends,’ ‘plans,’ ‘believes,’ ‘seeks,’ ‘estimates,’ and similar expressions are supposed to determine ahead-looking statements. These statements don’t seem to be guarantees of future performance and are area to general and unknown hazards, uncertainties, and other components, some of that are past the enterprise’s manage, are intricate to foretell, and will trigger actual effects to vary materially from these expressed or forecasted in the forward-looking statements. The business cautions protection holders and potential protection holders now not to region undue reliance on these ahead-searching statements, which replicate the view of the enterprise only as of the date of this announcement. The forward-looking statements made in this announcement relate handiest to events as of the date on which the statements are made. The company will not undertake any responsibility to unencumber publicly any revisions or updates to these forward-searching statements to reflect routine, circumstances, or unanticipated events taking place after the date of this announcement apart from as required by using law or through any applicable regulatory authority. commonly asked Questions and answers for Silence standard Shareholders:
what’s the relationship between the business’s normal Shares and ADSs?each advertisements is a tradeable safety representing three of the business’s common Shares. The ADSs had been accepted for buying and selling on Nasdaq under the ticker symbol: SLN. The cost of each ads is denominated in US greenbacks. What does it charge to exchange normal Shares into ADSs?There should be an issuance fee of up to US$5.00 per a hundred ADSs (or potion thereof) charged through The financial institution of long island Mellon for the issuance of the ADSs. The trade of your dematerialised commonplace Shares will should be managed by using your broking service as typical Shares deserve to be transferred electronically to The financial institution of new york Mellon ahead of the issuance of ADSs. Your selected broking service may also levy an administrative can charge for managing the trade method. How lengthy does it take and is dematerialisation quintessential?The financial institution of long island Mellon typically can also be expected to convey ADSs to your broking service within two enterprise days of receiving an electronic transfer of common Shares from your broker. youngsters, before this may turn up, in case you cling your general Shares in certificated form, you’ll should ship your share certificate and a signed stock deposit kind to your broker who will then should manipulate the "dematerialisation" manner vital to change your shares into digital kind. The timescale for this will rely upon your broking service but may still be anticipated to take about every week. I don’t have a broking service – do I really need one?sure, change into ADSs will require the counsel of a broker. Please check with "Notes for Shareholders". Is there a cost to hold ADSs?The financial institution of manhattan Mellon may can charge an annual Depositary service charge of up to US$0.05 per ads. this is typically gathered from the broking service or different intermediary that holds the ADSs in your behalf. Your broking service can also pass this fee on to you directly or it could be part of the annual charge that you pay to keep your brokerage account.
How do I alternate my typical Shares into ADSs?The manner set out on right here pages explains what you need to do to opt for an appropriate broker account and summarises the instructions that you should supply to your broking service with the intention to trade your commonplace Shares into ADSs. Please confer with "Notes for Brokers" which we imply you ship to your broker in case you are interested in changing average Shares for ADSs. Do I should alternate my normal Shares into ADSs?No, the company’s standard Shares will continue to trade on the goal market of the London inventory change plc. in case you do not need to grasp ADSs however are looking to continue to be a shareholder of Silence then no action is required. Are all ordinary Shares eligible to be deposited for start of ADSs?No.  general Shares which are owned by an govt officer or director or different person that can be considered an “affiliate” of the company under U.S. securities legislations and general Shares that have been got in a personal placement and have been held for under a year are frequently now not eligible to be deposited.  in case your ordinary Shares fall into one of these classes, please contact for extra suggestions on even if you will be allowed to deposit and under what situations. Notes for Shareholders: manner for changing regular Shares into ADSs:
Step 1: opt for a broker with US listed securities buying and selling potential.  in case you don’t have already got an account with a broker, you can be capable of open one both on-line or via banks and building societies which offer broking features. You need to be sure that the broker and type of account on offer is in a position to holding and trading US listed securities. frequently probably the most simple account offered is for UK listed shares only so you will should opt for an account that offers you the skill to buy and sell US listed shares. Please make certain that you check with your broking service that they could dangle Silence Therapeutics plc ADSs and have a DTC participant account. Step 2: you’ll should contact your broker and ask them the way to transfer your present certificated or dematerialised standard Shares into your account. in case you grasp actual share certificates, you will need to send them, together with a accomplished stock deposit kind to your broking service. The broking service have to come up with the necessary inventory deposit form and directions.  When the broker receives the share certificates, they are going to deserve to "dematerialise" the shares into electronic form so that they’re held electronically via the broker within CREST (the valuable securities depository that holds UK and Irish equities, operated via Euroclear UK & ireland restricted). When accomplished, your broking service can then deal with the change into ADSs. in case you already hold your normal Shares in dematerialised form in CREST, which you can organize for these to be delivered by means of the CREST gadget to the broking service coping with the advertisements change. Step three: Your broker will deserve to contact The financial institution of new york Mellon through e mail to prepare for the change of your commonplace Shares into ADSs tradeable on Nasdaq. you are going to acquire one ads for each 3 usual Shares that you hold and decide to deposit.
The contact details for The financial institution of long island Mellon, along with details of the conversion procedure are set out within the "Notes for Brokers" and the "Silence Therapeutics plc – UK ADR advent – SDRT Certification" set out on here pages. We suggest that you simply ship these to your broking service. Notes for Brokers: Conversion of standard Shares into ADSs tradeable on Nasdaq commonplace Shares are traded on aim below the ticker: SLN. Silence Therapeutics’ ADSs are listed and traded on Nasdaq beneath the ticker: SLN.
each adverts represents three average Shares. typical Shares will also be exchanged into the equal variety of ADSs via the business’s Depositary bank, The financial institution of long island Mellon. as soon as exchanged, the  ADSs are tradeable by the use of Nasdaq. The company’s registrar, link Asset services constrained, keeps the enterprise’s shareholder register and general Shares may also be held and transferred inside CREST. hence, you’re capable of obtain certificated average Shares and deposit these into CREST by the use of the regular CREST share deposit method. which you could then transfer the usual Shares to the CREST account of The bank of ny Mellon, performing through the workplace found in the united kingdom, for birth of ADSs. The newly created ADSs will then be transferred lower back to your nominated DTC account. The bank of new york Mellon’s CREST account particulars are as follows:
CREST participant id: BO011 Please use the under particulars for shares held electronically: BIC IRVTGB2X Safekeeping account 144029 prior to initiating a CREST transfer to BNY Mellon, please contact The financial institution of big apple Mellon crew with the aid of e-mail by means
To assist your communications with The bank of big apple Mellon we have developed the connected "Silence Therapeutics plc – UK ads creation – SDRT Certification", which sets out all the information that you’ll should ship to The financial institution of big apple Mellon to effect the trade of normal Shares into ADSs. Please finished and ship this kind to The bank of new york Mellon by using e mail to provoke the trade method. charges/taxes payable: The financial institution of ny Mellon expenses an advertisements issuance price of as much as US$5.00 per 100 ADSs (or element thereof). as the business’s normal Shares are at the moment admitted to trading on intention, no stamp responsibility reserve tax (SDRT) is payable. Ratio: every ads represents 3 common Shares. Fractional ADSs can’t be issued. therefore, the variety of standard Shares transmitted inside CREST to The bank of manhattan Mellon ought to be a multiple of 3.  Spare common Shares can either be retained in CREST or re-issued to your client in certificated form. Such re-issued common Shares will continue to be on the company’s shareholder register, registered in your customer’s identify (or in a nominee’s name, as applicable).   The issuance charge may still be paid in boost via Fedwire to: BNY Mellon ABA:021000018DR business Sub A/C:GLA 111 594Attn:DR Dept.Ref: Issuance payment of _______ ADSs of Silence Therapeutics The bank of long island Mellon, performing through an office observed within the united kingdom, as Custodian requires the Silence Therapeutics plc – UK ads creation – SDRT Certification to be e-mailed as a PDF file in a secured format to In the e mail discipline container, please state: SILENCE THERAPEUTICS PLC – UK ads creation – SDRT CERTIFICATION.
Please be sure this form is to your CREST agent’s headed paper.  Please fill all fields by means of typing and best use handwriting for the Signatures at the backside of the web page. Any questions should be directed to SILENCE THERAPEUTICS PLC – UK ads introduction – SDRT CERTIFICATION 1Crest reference of the trade 2ISIN number 3Trade Date as in CREST 4Settlement Date as in CREST 5Ratio (e.g.: "3:1" where 3 UK regular shares are converted to 1 adverts) 6Nominal 7Stampable Consideration quantity – obligatory field for Stamp applicable ISIN’s 8Stock fee 9Name of broking service 10Broker’s DTC Participant Account 11Shareholder/customer Account No. at broker 12Contact person / quantity 13Result of option sure / No 14CREST Participant identification 15SDRT (please most effective mark one field on the appropriate with an "X"): 161.5% 171% 18SDRT exempt 19Indemnity  SDRT notice: it’s required that the broker alleges in CREST GUI a announcement of SDRT if applicable: Please include the stamp status and Stampable Consideration. Signature …………………………………………  Signature ………………………………………
identify ………………………………………………  name ………………………………………… Submitting a claim the mandatory documentation and proof of possession and entitlement that you simply must submit to support your claim might be recognized on the kind. Required documentation The documentation required is dependent upon the class of claim you’re making. individual claims tips and documents requested may additionally consist of: Two styles of legitimate id for each claimant (comparable to a passport, driver’s license, or birth certificate) issued by way of distinct executive corporations (federal, provincial/territorial, municipal or local equivalent overseas):
One have to undergo the claimant’s photo.
One should encompass the claimant’s latest handle.

An common bank passbook or bank observation, if the claim is for an account
Proof of funding
Proof that the steadiness holder once resided at the address stated in our data.
estate claims suggestions and documents requested might also include: An normal bank passbook or financial institution commentary, if the declare is for an account
Proof of funding
Proof that the stability holder as soon as resided at the tackle stated in our information
Any consultant who’s licensed to settle the estate (reminiscent of an executor, trustee or liquidator) should post here documentation together with the claim: Two types of legitimate identification for every claimant (such as a passport, driver’s license, or delivery certificate) issued by different government businesses (federal, provincial/territorial, municipal or local equivalent abroad):
One have to endure the claimant’s image.
One must include the claimant’s present handle.

facts that you are licensed to behave on behalf of the property
the necessary criminal documentation regarding the steadiness holder will fluctuate, reckoning on whether that they had a last Will and testomony and which province they lived in at the time of dying. selected examples include: dying certificates
final Will and testament
Will Search Certificates (Quebec handiest)
Proof of Probate/certificate of Appointment of property Trustee with a Will
statement of Heredity or Letters of Verification (Quebec simplest)
Letters of Administration/certificates of Appointment of estate Trustee without a Will
criminal files submitted to the bank of Canada are usually not returned to claimants. We strongly suggest that most effective licensed or notarized copies of prison documents be submitted with a claim. Photocopies will not be authorized. other claims tips and files requested can also consist of: fame of the company (lively or dissolved service provider, for example)
Proof of signing authority
An original bank passbook or bank remark, if the declare is for an account
Proof of funding
Proof that the company’s tackle fits the advice listed on our unclaimed steadiness registry
the required documentation will vary, depending on the category of balance and the class and status of the corporation holding the stability. as an example, if the business has been dissolved or is inactive, it must be revived to ensure that the financial institution of Canada to proceed with the declare; documentation confirming the repute of the business can be required. (in any other case, all dollars for dissolved/inactive enterprise entities vest with the Crown). To learn how to revive an organization, please contact the relevant provincial company registry workplace or Innovation, Science and economic construction Canada. certain examples of documentation may additionally consist of: company Profile
Registered Charity/Registered Non-profit counsel Return
association Bylaws
Minutes of most contemporary Annual universal assembly
Partnership agreement
GST/HST Registration
Proof of possession and entitlement You need to demonstrate the stability-to-owner relationship by using featuring assisting files comparable to an account passbook, bank statements, the long-established instrument, and so on. The files required for the class of claim you’re making could be listed on the declare form generated through the on-line declare submission system. if you are unable to supply proof of possession and entitlement, you can be required to obtain a Bond of Indemnity (BofI) to guarantee the declare and to give the financial institution with recourse should still the claim in consequence be found invalid. If a BofI is required, further directions should be provided via the financial institution of Canada after your claim has been entirely reviewed. You may additionally incur costs as you attain the imperative criminal facts proving your possession..

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